Title: Executive
Role:
To execute activities related to R&D Peptide Process Development & Scale-ups, along with a group comprising of Research Officers/ Research Assistants in co-ordination with Team/Group Leader
Details of Previous Work Experience (Mandatory Requirement)
- Literature search and ROS (Route of Synthesis) finalization
- Basic knowledge of Orthogonal protected amino acid and Peptide.
- Solid phase peptide Synthesis.
- Handling of hazardous chemical like Trifluoroacetic acid.
- Knowledge of handling of analytical HPLC.
- Purification of Peptide using preparative HPLC.
- Preparative column packing and usage.
- Scale up experience
- Computer literacy etc.
Job Description:
● Literature search with respect to assigned project and finalizing the non-infringing synthetic route
● Experimentation (Process development, DoE study, optimization and validation).
● Purification of Peptide and knowledge of lyophilisation of pure solution.
● Handling of analytical HPLC and preparation of buffer.
● Characterisation of Peptide using HRMS,2D NMR, IR, Peptide mapping and sequencing.
● Preparation of Technology transfer documents.
● Scaling-up of process developed at R&D.
● Assisting to RA in filing DMF.
● General Laboratory Management etc.